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September 5, 2006

A little hope for the children of Africa: Swedish HIV vaccine looks good

Filed under: Afrika — limewoody @ 4:07 pm

2006-08-31 07:49) A Swedish HIV vaccine study being conducted by the Karolinska Institute, Karolinska University Hospital and Smittskyddsinstitutet (SMI) has shown surprisingly positive results. Over 90 percent of the subjects in the Phase I study conducted in Sweden have developed immunity against HIV.

By Alannah Eames


According to Professor Eric Sandström at Karolinska University Hospital, “Never has such a good result been seen with a vaccine of this type.”

The trial subjects were vaccinated on three occasions with this vaccine using a needle-free method of injection. This vaccine-based HIV vaccine is produced by the US National Institutes of Health and was donated for use in this Swedish study.

Scientists now hope to follow up the Swedish study with a larger phase I or phase 2 study in Tanzania, planned to commence this autumn, in order to corroborate the Swedish results on African subjects and to help train Tanzanians to carry out parts of the study, including sophisticated laboratory examinations, on site.

The project is being led by Karolinska Institute professors Gunnel Biberfeld and Britta Wahren at the SMI and Eric Sandström at the Karolinska University Hospital.

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